Selenium deficiency is a significant health concern in regions of China where the soil contains minimal selenium, leading to insufficient dietary intake. This deficiency is closely linked to Keshan Disease, a potentially fatal cardiomyopathy primarily affecting rural populations. Named after the Keshan County in Heilongjiang Province, where it was first identified, the disease is characterized by an enlarged heart and impaired cardiac function, which can result in heart failure or sudden death.
Keshan Disease is most prevalent in areas where selenium intake is critically low, with men consuming less than 19 micrograms per day and women less than 13 micrograms. These levels are well below the recommended dietary intake, which exacerbates the risk of developing the disease. The connection between selenium deficiency and Keshan Disease underscores the importance of adequate selenium levels for maintaining cardiovascular health. Despite improvements in nutrition and public health interventions, cases still emerge in regions with persistently low soil selenium content, highlighting the ongoing need for selenium supplementation and soil enrichment programs to prevent this life-threatening condition.
Impact of Selenium Deficiency on Keshan Disease in Rural China
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